BDBM50142562 11-(1-Methyl-1H-pyrrol-2-yl)-9-(4-methyl-thiazol-2-yl)-6,7-dihydro-5H-2,7a-diaza-dibenzo[a,c]cyclohepten-8-one::CHEMBL47295

SMILES: Cc1csc(n1)-c1cc(-c2cccn2C)c2-c3cnccc3CCCn2c1=O

InChI Key: InChIKey=QVKRJAGEEGDZOB-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50142562   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA receptor alpha-3/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50142562 (11-(1-Methyl-1H-pyrrol-2-yl)-9-(4-methyl-thiazol-2...) Show SMILES Cc1csc(n1)-c1cc(-c2cccn2C)c2-c3cnccc3CCCn2c1=O Show InChI InChI=1S/C22H20N4OS/c1-14-13-28-21(24-14)17-11-16(19-6-4-9-25(19)2)20-18-12-23-8-7-15(18)5-3-10-26(20)22(17)27/h4,6-9,11-13H,3,5,10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Neuroscience Research Centre Curated by ChEMBL					Assay Description Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha1-beta3-gamma2 expressed in L(tk) cells by [3H]-Ro-15-1788 displacement...				Bioorg Med Chem Lett 14: 1679-82 (2004) Article DOI: 10.1016/j.bmcl.2004.01.057 BindingDB Entry DOI: 10.7270/Q27D2TK7
					More data for this Ligand-Target Pair
GABA receptor alpha-1/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50142562 (11-(1-Methyl-1H-pyrrol-2-yl)-9-(4-methyl-thiazol-2...) Show SMILES Cc1csc(n1)-c1cc(-c2cccn2C)c2-c3cnccc3CCCn2c1=O Show InChI InChI=1S/C22H20N4OS/c1-14-13-28-21(24-14)17-11-16(19-6-4-9-25(19)2)20-18-12-23-8-7-15(18)5-3-10-26(20)22(17)27/h4,6-9,11-13H,3,5,10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Neuroscience Research Centre Curated by ChEMBL					Assay Description Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha3-beta3-gamma2 expressed in L(tk) cells by [3H]-Ro-15-1788 displacement...				Bioorg Med Chem Lett 14: 1679-82 (2004) Article DOI: 10.1016/j.bmcl.2004.01.057 BindingDB Entry DOI: 10.7270/Q27D2TK7
					More data for this Ligand-Target Pair