BDBM50142568 9-(4-Methyl-thiazol-2-yl)-11-pyridazin-4-yl-6,7-dihydro-5H-2,7a-diaza-dibenzo[a,c]cyclohepten-8-one::CHEMBL44428

SMILES: Cc1csc(n1)-c1cc(-c2ccnnc2)c2-c3cnccc3CCCn2c1=O

InChI Key: InChIKey=XQXFLYIUHYKDHV-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50142568   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA receptor alpha-3/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50142568 (9-(4-Methyl-thiazol-2-yl)-11-pyridazin-4-yl-6,7-di...) Show SMILES Cc1csc(n1)-c1cc(-c2ccnnc2)c2-c3cnccc3CCCn2c1=O Show InChI InChI=1S/C21H17N5OS/c1-13-12-28-20(25-13)17-9-16(15-5-7-23-24-10-15)19-18-11-22-6-4-14(18)3-2-8-26(19)21(17)27/h4-7,9-12H,2-3,8H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Neuroscience Research Centre Curated by ChEMBL					Assay Description Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha3-beta3-gamma2 expressed in L(tk) cells by [3H]-Ro-15-1788 displacement...				Bioorg Med Chem Lett 14: 1679-82 (2004) Article DOI: 10.1016/j.bmcl.2004.01.057 BindingDB Entry DOI: 10.7270/Q27D2TK7
					More data for this Ligand-Target Pair
GABA receptor alpha-1/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50142568 (9-(4-Methyl-thiazol-2-yl)-11-pyridazin-4-yl-6,7-di...) Show SMILES Cc1csc(n1)-c1cc(-c2ccnnc2)c2-c3cnccc3CCCn2c1=O Show InChI InChI=1S/C21H17N5OS/c1-13-12-28-20(25-13)17-9-16(15-5-7-23-24-10-15)19-18-11-22-6-4-14(18)3-2-8-26(19)21(17)27/h4-7,9-12H,2-3,8H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Neuroscience Research Centre Curated by ChEMBL					Assay Description Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha3-beta3-gamma2 expressed in L(tk) cells by [3H]-Ro-15-1788 displacement...				Bioorg Med Chem Lett 14: 1679-82 (2004) Article DOI: 10.1016/j.bmcl.2004.01.057 BindingDB Entry DOI: 10.7270/Q27D2TK7
					More data for this Ligand-Target Pair