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BDBM50142571 11-Furan-3-yl-9-(4-methyl-thiazol-2-yl)-6,7-dihydro-5H-2,7a-diaza-dibenzo[a,c]cyclohepten-8-one::CHEMBL44065

SMILES: Cc1csc(n1)-c1cc(-c2ccoc2)c2-c3cnccc3CCCn2c1=O

InChI Key: InChIKey=DSKYZAOKCWQIRI-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50142571   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
GABA receptor alpha-1/beta-3/gamma-2 subunit


(Homo sapiens (Human))
BDBM50142571
PNG
(11-Furan-3-yl-9-(4-methyl-thiazol-2-yl)-6,7-dihydr...)
Show SMILES Cc1csc(n1)-c1cc(-c2ccoc2)c2-c3cnccc3CCCn2c1=O
Show InChI InChI=1S/C21H17N3O2S/c1-13-12-27-20(23-13)17-9-16(15-5-8-26-11-15)19-18-10-22-6-4-14(18)3-2-7-24(19)21(17)25/h4-6,8-12H,2-3,7H2,1H3
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
3.90n/an/an/an/an/an/an/an/a



The Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha3-beta3-gamma2 expressed in L(tk) cells by [3H]-Ro-15-1788 displacement...


Bioorg Med Chem Lett 14: 1679-82 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.057
BindingDB Entry DOI: 10.7270/Q27D2TK7
More data for this
Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit


(Homo sapiens (Human))
BDBM50142571
PNG
(11-Furan-3-yl-9-(4-methyl-thiazol-2-yl)-6,7-dihydr...)
Show SMILES Cc1csc(n1)-c1cc(-c2ccoc2)c2-c3cnccc3CCCn2c1=O
Show InChI InChI=1S/C21H17N3O2S/c1-13-12-27-20(23-13)17-9-16(15-5-8-26-11-15)19-18-10-22-6-4-14(18)3-2-7-24(19)21(17)25/h4-6,8-12H,2-3,7H2,1H3
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
4.40n/an/an/an/an/an/an/an/a



The Neuroscience Research Centre

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha1-beta3-gamma2 expressed in L(tk) cells by [3H]-Ro-15-1788 displacement...


Bioorg Med Chem Lett 14: 1679-82 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.057
BindingDB Entry DOI: 10.7270/Q27D2TK7
More data for this
Ligand-Target Pair