BDBM50142951 4-[3-({[2,4-Dichloro-3-(4-imidazol-1-yl-2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-ureido]-N-pyridin-4-yl-benzamide; trihydrochloride::CHEMBL542598

SMILES: CN(C(=O)CNC(=O)Nc1ccc(cc1)C(=O)Nc1ccncc1)c1ccc(Cl)c(COc2cccc3c(cc(C)nc23)-n2ccnc2)c1Cl

InChI Key: InChIKey=QGYHWLVUEIIIEA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50142951   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
BDKRB2 (Homo sapiens (Human))	BDBM50142951 (4-[3-({[2,4-Dichloro-3-(4-imidazol-1-yl-2-methyl-q...) Show SMILES CN(C(=O)CNC(=O)Nc1ccc(cc1)C(=O)Nc1ccncc1)c1ccc(Cl)c(COc2cccc3c(cc(C)nc23)-n2ccnc2)c1Cl Show InChI InChI=1S/C36H30Cl2N8O4/c1-22-18-30(46-17-16-40-21-46)26-4-3-5-31(34(26)42-22)50-20-27-28(37)10-11-29(33(27)38)45(2)32(47)19-41-36(49)44-24-8-6-23(7-9-24)35(48)43-25-12-14-39-15-13-25/h3-18,21H,19-20H2,1-2H3,(H,39,43,48)(H2,41,44,49)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory activity towards bradykinin receptor B2 using [3H]BK (0.06 nM) as a radioligand in guinea pig ileum membrane preparation				J Med Chem 47: 1617-30 (2004) Article DOI: 10.1021/jm030159x BindingDB Entry DOI: 10.7270/Q2P55P89
					More data for this Ligand-Target Pair
BDKRB2 (Homo sapiens (Human))	BDBM50142951 (4-[3-({[2,4-Dichloro-3-(4-imidazol-1-yl-2-methyl-q...) Show SMILES CN(C(=O)CNC(=O)Nc1ccc(cc1)C(=O)Nc1ccncc1)c1ccc(Cl)c(COc2cccc3c(cc(C)nc23)-n2ccnc2)c1Cl Show InChI InChI=1S/C36H30Cl2N8O4/c1-22-18-30(46-17-16-40-21-46)26-4-3-5-31(34(26)42-22)50-20-27-28(37)10-11-29(33(27)38)45(2)32(47)19-41-36(49)44-24-8-6-23(7-9-24)35(48)43-25-12-14-39-15-13-25/h3-18,21H,19-20H2,1-2H3,(H,39,43,48)(H2,41,44,49)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory activity towards human bradykinin receptor B2 expressed in CHO cells using [3H]BK (1.0 nM) as a radioligand				J Med Chem 47: 1617-30 (2004) Article DOI: 10.1021/jm030159x BindingDB Entry DOI: 10.7270/Q2P55P89
					More data for this Ligand-Target Pair