BDBM50143913 4-(3-Adamantan-1-yl-ureido)-butyric acid pentyl ester::CHEMBL302505

SMILES: CCCCCOC(=O)CCCNC(=O)NC12CC3CC(CC(C3)C1)C2

InChI Key: InChIKey=NQJCTWSXXZBQGX-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50143913   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Soluble epoxide hydrolase (sEH) (Mus musculus (Mouse))	BDBM50143913 (4-(3-Adamantan-1-yl-ureido)-butyric acid pentyl es...) Show SMILES CCCCCOC(=O)CCCNC(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:22:17:24:21.23.20,22:21:24:17.16.18,THB:16:15:17.18.22:20,16:17:15.23.24:20| Show InChI InChI=1S/C20H34N2O3/c1-2-3-4-8-25-18(23)6-5-7-21-19(24)22-20-12-15-9-16(13-20)11-17(10-15)14-20/h15-17H,2-14H2,1H3,(H2,21,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
University of California-Davis Curated by ChEMBL					Assay Description Tested for 50 % inhibitory concentration against mouse soluble epoxide hydrolase (sEH)				J Med Chem 47: 2110-22 (2004) Article DOI: 10.1021/jm030514j BindingDB Entry DOI: 10.7270/Q29Z94BM
					More data for this Ligand-Target Pair
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50143913 (4-(3-Adamantan-1-yl-ureido)-butyric acid pentyl es...) Show SMILES CCCCCOC(=O)CCCNC(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:22:17:24:21.23.20,22:21:24:17.16.18,THB:16:15:17.18.22:20,16:17:15.23.24:20| Show InChI InChI=1S/C20H34N2O3/c1-2-3-4-8-25-18(23)6-5-7-21-19(24)22-20-12-15-9-16(13-20)11-17(10-15)14-20/h15-17H,2-14H2,1H3,(H2,21,22,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
University of California-Davis Curated by ChEMBL					Assay Description Tested for 50 % inhibitory concentration against human soluble epoxide hydrolase (sEH)				J Med Chem 47: 2110-22 (2004) Article DOI: 10.1021/jm030514j BindingDB Entry DOI: 10.7270/Q29Z94BM
					More data for this Ligand-Target Pair
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50143913 (4-(3-Adamantan-1-yl-ureido)-butyric acid pentyl es...) Show SMILES CCCCCOC(=O)CCCNC(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:22:17:24:21.23.20,22:21:24:17.16.18,THB:16:15:17.18.22:20,16:17:15.23.24:20| Show InChI InChI=1S/C20H34N2O3/c1-2-3-4-8-25-18(23)6-5-7-21-19(24)22-20-12-15-9-16(13-20)11-17(10-15)14-20/h15-17H,2-14H2,1H3,(H2,21,22,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase pre-incubated for 5 mins at 30 degC before CMNPC fluorescent substrate addition by fluorimetric assay				Bioorg Med Chem Lett 22: 5889-92 (2012) Article DOI: 10.1016/j.bmcl.2012.07.074 BindingDB Entry DOI: 10.7270/Q2TH8NSF
					More data for this Ligand-Target Pair
Soluble epoxide hydrolase (sEH) (Mus musculus (Mouse))	BDBM50143913 (4-(3-Adamantan-1-yl-ureido)-butyric acid pentyl es...) Show SMILES CCCCCOC(=O)CCCNC(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:22:17:24:21.23.20,22:21:24:17.16.18,THB:16:15:17.18.22:20,16:17:15.23.24:20| Show InChI InChI=1S/C20H34N2O3/c1-2-3-4-8-25-18(23)6-5-7-21-19(24)22-20-12-15-9-16(13-20)11-17(10-15)14-20/h15-17H,2-14H2,1H3,(H2,21,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Department of Entomology and University of California Davis Cancer Center Curated by ChEMBL					Assay Description Inhibitory concentration against mouse soluble epoxide hydrolase (sEH) at 0.12 uM				J Med Chem 48: 3621-9 (2005) Article DOI: 10.1021/jm0500929 BindingDB Entry DOI: 10.7270/Q2D799X0
					More data for this Ligand-Target Pair
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50143913 (4-(3-Adamantan-1-yl-ureido)-butyric acid pentyl es...) Show SMILES CCCCCOC(=O)CCCNC(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:22:17:24:21.23.20,22:21:24:17.16.18,THB:16:15:17.18.22:20,16:17:15.23.24:20| Show InChI InChI=1S/C20H34N2O3/c1-2-3-4-8-25-18(23)6-5-7-21-19(24)22-20-12-15-9-16(13-20)11-17(10-15)14-20/h15-17H,2-14H2,1H3,(H2,21,22,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Department of Entomology and University of California Davis Cancer Center Curated by ChEMBL					Assay Description Inhibitory concentration against human soluble epoxide hydrolase (sEH) at 0.24 uM				J Med Chem 48: 3621-9 (2005) Article DOI: 10.1021/jm0500929 BindingDB Entry DOI: 10.7270/Q2D799X0
					More data for this Ligand-Target Pair