BDBM50143925 1-Cyclohexyl-3-decyl-urea::CHEMBL67158::N-CYCLOHEXYL-N'-DECYLUREA::US8815951, 153
SMILES: CCCCCCCCCCNC(=O)NC1CCCCC1
InChI Key: InChIKey=LPXYBLIRYGCMPQ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epoxide hydrolase (MsEH) (Mus musculus (Mouse)) | BDBM50143925![]() (1-Cyclohexyl-3-decyl-urea | CHEMBL67158 | N-CYCLOH...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
The Regents of the University of California US Patent | Assay Description The invention also provide methods for assaying for epoxide hydrolase activity as diagnostic assay to identify individuals at increased risk for hype... | US Patent US8815951 (2014) BindingDB Entry DOI: 10.7270/Q2BP01G9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human)) | BDBM50143925![]() (1-Cyclohexyl-3-decyl-urea | CHEMBL67158 | N-CYCLOH...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California-Davis Curated by ChEMBL | Assay Description Tested for 50 % inhibitory concentration against human soluble epoxide hydrolase (sEH) | J Med Chem 47: 2110-22 (2004) Article DOI: 10.1021/jm030514j BindingDB Entry DOI: 10.7270/Q29Z94BM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Soluble epoxide hydrolase (sEH) (Mus musculus (Mouse)) | BDBM50143925![]() (1-Cyclohexyl-3-decyl-urea | CHEMBL67158 | N-CYCLOH...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California-Davis Curated by ChEMBL | Assay Description Tested for 50 % inhibitory concentration against mouse soluble epoxide hydrolase (sEH) | J Med Chem 47: 2110-22 (2004) Article DOI: 10.1021/jm030514j BindingDB Entry DOI: 10.7270/Q29Z94BM | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Epoxide hydrolase 1 (Homo sapiens (Human)) | BDBM50143925![]() (1-Cyclohexyl-3-decyl-urea | CHEMBL67158 | N-CYCLOH...) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
The Regents of the University of California US Patent | Assay Description The invention also provide methods for assaying for epoxide hydrolase activity as diagnostic assay to identify individuals at increased risk for hype... | US Patent US8815951 (2014) BindingDB Entry DOI: 10.7270/Q2BP01G9 | |||||||||||
More data for this Ligand-Target Pair |