BDBM50143927 8-[4-(3-Adamantan-1-yl-ureido)-butyryloxy]-octanoic acid ethyl ester::CHEMBL302704

SMILES: CCOC(=O)CCCCCCCOC(=O)CCCNC(=O)NC12CC3CC(CC(C3)C1)C2

InChI Key: InChIKey=TXTMGXWASHEWKO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50143927   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50143927 (8-[4-(3-Adamantan-1-yl-ureido)-butyryloxy]-octanoi...) Show SMILES CCOC(=O)CCCCCCCOC(=O)CCCNC(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:29:24:31:28.30.27,29:28:31:24.23.25,THB:23:22:24.25.29:27,23:24:22.30.31:27| Show InChI InChI=1S/C25H42N2O5/c1-2-31-22(28)9-6-4-3-5-7-12-32-23(29)10-8-11-26-24(30)27-25-16-19-13-20(17-25)15-21(14-19)18-25/h19-21H,2-18H2,1H3,(H2,26,27,30)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
University of California-Davis Curated by ChEMBL					Assay Description Tested for 50 % inhibitory concentration against human soluble epoxide hydrolase (sEH)				J Med Chem 47: 2110-22 (2004) Article DOI: 10.1021/jm030514j BindingDB Entry DOI: 10.7270/Q29Z94BM
					More data for this Ligand-Target Pair
Soluble epoxide hydrolase (sEH) (Mus musculus (Mouse))	BDBM50143927 (8-[4-(3-Adamantan-1-yl-ureido)-butyryloxy]-octanoi...) Show SMILES CCOC(=O)CCCCCCCOC(=O)CCCNC(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:29:24:31:28.30.27,29:28:31:24.23.25,THB:23:22:24.25.29:27,23:24:22.30.31:27| Show InChI InChI=1S/C25H42N2O5/c1-2-31-22(28)9-6-4-3-5-7-12-32-23(29)10-8-11-26-24(30)27-25-16-19-13-20(17-25)15-21(14-19)18-25/h19-21H,2-18H2,1H3,(H2,26,27,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
University of California-Davis Curated by ChEMBL					Assay Description Tested for 50 % inhibitory concentration against mouse soluble epoxide hydrolase (sEH)				J Med Chem 47: 2110-22 (2004) Article DOI: 10.1021/jm030514j BindingDB Entry DOI: 10.7270/Q29Z94BM
					More data for this Ligand-Target Pair