null

SMILES: CS(=O)(=O)Nc1ccc-2c(c1)C(Oc1cccc(OC(F)F)c-21)c1ccccc1

InChI Key: InChIKey=WFSBONJXUAXVJH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50144173   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM50144173 (CHEMBL65221 | N-(1-Difluoromethoxy-6-phenyl-6H-ben...) Show SMILES CS(=O)(=O)Nc1ccc-2c(c1)C(Oc1cccc(OC(F)F)c-21)c1ccccc1 Show InChI InChI=1S/C21H17F2NO4S/c1-29(25,26)24-14-10-11-15-16(12-14)20(13-6-3-2-4-7-13)27-17-8-5-9-18(19(15)17)28-21(22)23/h2-12,20-21,24H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]estradiol from human estrogen receptor alpha				Bioorg Med Chem Lett 14: 2079-82 (2004) Article DOI: 10.1016/j.bmcl.2004.02.048 BindingDB Entry DOI: 10.7270/Q21V5FHJ
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50144173 (CHEMBL65221 | N-(1-Difluoromethoxy-6-phenyl-6H-ben...) Show SMILES CS(=O)(=O)Nc1ccc-2c(c1)C(Oc1cccc(OC(F)F)c-21)c1ccccc1 Show InChI InChI=1S/C21H17F2NO4S/c1-29(25,26)24-14-10-11-15-16(12-14)20(13-6-3-2-4-7-13)27-17-8-5-9-18(19(15)17)28-21(22)23/h2-12,20-21,24H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from human Androgen receptor				Bioorg Med Chem Lett 14: 2079-82 (2004) Article DOI: 10.1016/j.bmcl.2004.02.048 BindingDB Entry DOI: 10.7270/Q21V5FHJ
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50144173 (CHEMBL65221 | N-(1-Difluoromethoxy-6-phenyl-6H-ben...) Show SMILES CS(=O)(=O)Nc1ccc-2c(c1)C(Oc1cccc(OC(F)F)c-21)c1ccccc1 Show InChI InChI=1S/C21H17F2NO4S/c1-29(25,26)24-14-10-11-15-16(12-14)20(13-6-3-2-4-7-13)27-17-8-5-9-18(19(15)17)28-21(22)23/h2-12,20-21,24H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR); Value ranges from 9-12 nM				Bioorg Med Chem Lett 14: 2079-82 (2004) Article DOI: 10.1016/j.bmcl.2004.02.048 BindingDB Entry DOI: 10.7270/Q21V5FHJ
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50144173 (CHEMBL65221 | N-(1-Difluoromethoxy-6-phenyl-6H-ben...) Show SMILES CS(=O)(=O)Nc1ccc-2c(c1)C(Oc1cccc(OC(F)F)c-21)c1ccccc1 Show InChI InChI=1S/C21H17F2NO4S/c1-29(25,26)24-14-10-11-15-16(12-14)20(13-6-3-2-4-7-13)27-17-8-5-9-18(19(15)17)28-21(22)23/h2-12,20-21,24H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	367	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]progesterone from human Progesterone receptor				Bioorg Med Chem Lett 14: 2079-82 (2004) Article DOI: 10.1016/j.bmcl.2004.02.048 BindingDB Entry DOI: 10.7270/Q21V5FHJ
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50144173 (CHEMBL65221 | N-(1-Difluoromethoxy-6-phenyl-6H-ben...) Show SMILES CS(=O)(=O)Nc1ccc-2c(c1)C(Oc1cccc(OC(F)F)c-21)c1ccccc1 Show InChI InChI=1S/C21H17F2NO4S/c1-29(25,26)24-14-10-11-15-16(12-14)20(13-6-3-2-4-7-13)27-17-8-5-9-18(19(15)17)28-21(22)23/h2-12,20-21,24H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Effect on human Glucocorticoid receptor (GR) in a whole cell assay to measure functional cellular GR-antagonism (GRAF)				Bioorg Med Chem Lett 14: 2079-82 (2004) Article DOI: 10.1016/j.bmcl.2004.02.048 BindingDB Entry DOI: 10.7270/Q21V5FHJ
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50144173 (CHEMBL65221 | N-(1-Difluoromethoxy-6-phenyl-6H-ben...) Show SMILES CS(=O)(=O)Nc1ccc-2c(c1)C(Oc1cccc(OC(F)F)c-21)c1ccccc1 Show InChI InChI=1S/C21H17F2NO4S/c1-29(25,26)24-14-10-11-15-16(12-14)20(13-6-3-2-4-7-13)27-17-8-5-9-18(19(15)17)28-21(22)23/h2-12,20-21,24H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	162	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]aldosterone from human Mineralocorticoid receptor				Bioorg Med Chem Lett 14: 2079-82 (2004) Article DOI: 10.1016/j.bmcl.2004.02.048 BindingDB Entry DOI: 10.7270/Q21V5FHJ
					More data for this Ligand-Target Pair