null

SMILES: COc1cccc2OC(c3ccc(Cl)c(Cl)c3)c3cc(NS(C)(=O)=O)ccc3-c12

InChI Key: InChIKey=KULQOYWLHMRRIA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50144181   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50144181 (CHEMBL304877 | N-[6-(3,4-Dichloro-phenyl)-1-methox...) Show SMILES COc1cccc2OC(c3ccc(Cl)c(Cl)c3)c3cc(NS(C)(=O)=O)ccc3-c12 Show InChI InChI=1S/C21H17Cl2NO4S/c1-27-18-4-3-5-19-20(18)14-8-7-13(24-29(2,25)26)11-15(14)21(28-19)12-6-9-16(22)17(23)10-12/h3-11,21,24H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR); Value ranges from 3-4 nM				Bioorg Med Chem Lett 14: 2079-82 (2004) Article DOI: 10.1016/j.bmcl.2004.02.048 BindingDB Entry DOI: 10.7270/Q21V5FHJ
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50144181 (CHEMBL304877 | N-[6-(3,4-Dichloro-phenyl)-1-methox...) Show SMILES COc1cccc2OC(c3ccc(Cl)c(Cl)c3)c3cc(NS(C)(=O)=O)ccc3-c12 Show InChI InChI=1S/C21H17Cl2NO4S/c1-27-18-4-3-5-19-20(18)14-8-7-13(24-29(2,25)26)11-15(14)21(28-19)12-6-9-16(22)17(23)10-12/h3-11,21,24H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	378	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Effect on human Glucocorticoid receptor (GR) in a whole cell assay to measure functional cellular GR-antagonism (GRAF)				Bioorg Med Chem Lett 14: 2079-82 (2004) Article DOI: 10.1016/j.bmcl.2004.02.048 BindingDB Entry DOI: 10.7270/Q21V5FHJ
					More data for this Ligand-Target Pair