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SMILES: CCCN(c1nccc(n1)-c1c(OC)cc(OC)cc1OC)C1(CC1)c1cccs1

InChI Key: InChIKey=BBVBVFFELLROLS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50144190   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50144190
PNG
(CHEMBL302396 | Propyl-(1-thiophen-2-yl-cyclopropyl...)
Show SMILES CCCN(c1nccc(n1)-c1c(OC)cc(OC)cc1OC)C1(CC1)c1cccs1
Show InChI InChI=1S/C23H27N3O3S/c1-5-12-26(23(9-10-23)20-7-6-13-30-20)22-24-11-8-17(25-22)21-18(28-3)14-16(27-2)15-19(21)29-4/h6-8,11,13-15H,5,9-10,12H2,1-4H3
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 250n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc

Curated by ChEMBL


Assay Description
Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cells

Bioorg Med Chem Lett 14: 2083-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.053
BindingDB Entry DOI: 10.7270/Q2JH3KKJ
More data for this
Ligand-Target Pair