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SMILES: CCCN([C@H](C1CC1)c1ccccc1)c1nccc(n1)-c1c(OC)cc(OC)cc1OC

InChI Key: InChIKey=IFGNWUIDGZIYAU-VWLOTQADSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50144202   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50144202
PNG
(((R)-Cyclopropyl-phenyl-methyl)-propyl-[4-(2,4,6-t...)
Show SMILES CCCN([C@H](C1CC1)c1ccccc1)c1nccc(n1)-c1c(OC)cc(OC)cc1OC
Show InChI InChI=1S/C26H31N3O3/c1-5-15-29(25(19-11-12-19)18-9-7-6-8-10-18)26-27-14-13-21(28-26)24-22(31-3)16-20(30-2)17-23(24)32-4/h6-10,13-14,16-17,19,25H,5,11-12,15H2,1-4H3/t25-/m0/s1
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Article
PubMed
 240n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc

Curated by ChEMBL


Assay Description
Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cells

Bioorg Med Chem Lett 14: 2083-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.053
BindingDB Entry DOI: 10.7270/Q2JH3KKJ
More data for this
Ligand-Target Pair