BDBM50144943 (2R,3R,4R,5R)-5-(hydroxymethyl)-3-methyl-2-(9H-purin-9-yl)oxolane-3,4-diol::CHEMBL75343

SMILES: C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1cnc2cncnc12

InChI Key: InChIKey=HAUCHRMUNOHPHD-YJFSRANCSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50144943   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50144943 ((2R,3R,4R,5R)-5-(hydroxymethyl)-3-methyl-2-(9H-pur...) Show SMILES C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1cnc2cncnc12 Show InChI InChI=1S/C11H14N4O4/c1-11(18)8(17)7(3-16)19-10(11)15-5-14-6-2-12-4-13-9(6)15/h2,4-5,7-8,10,16-18H,3H2,1H3/t7-,8-,10-,11-/m1/s1	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV RNA replication				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair