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BDBM50145104 CHEMBL3763348

SMILES: O=c1[nH]nc2C(C(Nc3cccc1c23)c1cccnc1)c1cccnc1

InChI Key: InChIKey=SUVRIGMVTIDCKN-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145104   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50145104
PNG
(CHEMBL3763348)
Show SMILES O=c1[nH]nc2C(C(Nc3cccc1c23)c1cccnc1)c1cccnc1
Show InChI InChI=1S/C20H15N5O/c26-20-14-6-1-7-15-17(14)19(24-25-20)16(12-4-2-8-21-10-12)18(23-15)13-5-3-9-22-11-13/h1-11,16,18,23H,(H,25,26)
PDB
MMDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 18n/an/an/an/an/an/a



BioMarin Pharmaceutical Inc.

Curated by ChEMBL


Assay Description
Inhibition of human PARP1 using [3H]NAD as substrate after 1 min by microplate scintillation counting analysis

J Med Chem 59: 335-57 (2016)


BindingDB Entry DOI: 10.7270/Q2K35WJR
More data for this
Ligand-Target Pair