BDBM50145428 CHEMBL3764299

SMILES: CC(C)C1=CC[C@H](Cn2cc(CN(c3ncccn3)S(=O)(=O)c3ccc(N)cc3)nn2)[C@]11CCC(=O)C=C1

InChI Key: InChIKey=JNYLDCDQEZYRJA-HRFSGMKKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50145428   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 2 (Homo sapiens (Human))	BDBM50145428 (CHEMBL3764299) Show SMILES CC(C)C1=CC[C@H](Cn2cc(CN(c3ncccn3)S(=O)(=O)c3ccc(N)cc3)nn2)[C@]11CCC(=O)C=C1 |r,c:40,t:3| Show InChI InChI=1S/C27H31N7O3S/c1-19(2)25-9-4-20(27(25)12-10-23(35)11-13-27)16-33-17-22(31-32-33)18-34(26-29-14-3-15-30-26)38(36,37)24-7-5-21(28)6-8-24/h3,5-10,12,14-15,17,19-20H,4,11,13,16,18,28H2,1-2H3/t20-,27+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of full length human 11beta-HSD2 expressed in HEK293 cells using cortisone as substrate incubated for 2 hrs by HTRF assay in presence of N...				Eur J Med Chem 110: 126-32 (2016) BindingDB Entry DOI: 10.7270/Q28P62DG
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50145428 (CHEMBL3764299) Show SMILES CC(C)C1=CC[C@H](Cn2cc(CN(c3ncccn3)S(=O)(=O)c3ccc(N)cc3)nn2)[C@]11CCC(=O)C=C1 |r,c:40,t:3| Show InChI InChI=1S/C27H31N7O3S/c1-19(2)25-9-4-20(27(25)12-10-23(35)11-13-27)16-33-17-22(31-32-33)18-34(26-29-14-3-15-30-26)38(36,37)24-7-5-21(28)6-8-24/h3,5-10,12,14-15,17,19-20H,4,11,13,16,18,28H2,1-2H3/t20-,27+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of 11beta-HSD1 (unknown origin) using cortisol as substrate assessed as NADPH formation by fluorescent plate reader analysis				Eur J Med Chem 110: 126-32 (2016) BindingDB Entry DOI: 10.7270/Q28P62DG
					More data for this Ligand-Target Pair