BDBM50145443 CHEMBL3765321

SMILES: CC(C)C1=CC[C@H](C(=O)NCC2CCC3CC2C3(C)C)[C@]11CCC(=O)C=C1

InChI Key: InChIKey=UJXOMZLXTJJELJ-CLHTUNCFSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50145443   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 2 (Homo sapiens (Human))	BDBM50145443 (CHEMBL3765321) Show SMILES CC(C)C1=CC[C@H](C(=O)NCC2CCC3CC2C3(C)C)[C@]11CCC(=O)C=C1 |r,c:28,t:3,TLB:10:11:17:15| Show InChI InChI=1S/C24H35NO2/c1-15(2)19-7-8-20(24(19)11-9-18(26)10-12-24)22(27)25-14-16-5-6-17-13-21(16)23(17,3)4/h7,9,11,15-17,20-21H,5-6,8,10,12-14H2,1-4H3,(H,25,27)/t16?,17?,20-,21?,24-/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of full length human 11beta-HSD2 expressed in HEK293 cells using cortisone as substrate incubated for 2 hrs by HTRF assay in presence of N...				Eur J Med Chem 110: 126-32 (2016) BindingDB Entry DOI: 10.7270/Q28P62DG
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50145443 (CHEMBL3765321) Show SMILES CC(C)C1=CC[C@H](C(=O)NCC2CCC3CC2C3(C)C)[C@]11CCC(=O)C=C1 |r,c:28,t:3,TLB:10:11:17:15| Show InChI InChI=1S/C24H35NO2/c1-15(2)19-7-8-20(24(19)11-9-18(26)10-12-24)22(27)25-14-16-5-6-17-13-21(16)23(17,3)4/h7,9,11,15-17,20-21H,5-6,8,10,12-14H2,1-4H3,(H,25,27)/t16?,17?,20-,21?,24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of 11beta-HSD1 (unknown origin) using cortisol as substrate assessed as NADPH formation by fluorescent plate reader analysis				Eur J Med Chem 110: 126-32 (2016) BindingDB Entry DOI: 10.7270/Q28P62DG
					More data for this Ligand-Target Pair