BDBM50145468 CHEMBL3764521

SMILES: CC(C)[C@@H]1CC[C@H](CO)[C@]11CC[C@@](C)(O)[C@@H](O)C1

InChI Key: InChIKey=OTTDIBJIEXQHKJ-GZBLMMOJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145468   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50145468 (CHEMBL3764521) Show SMILES CC(C)[C@@H]1CC[C@H](CO)[C@]11CC[C@@](C)(O)[C@@H](O)C1 |r| Show InChI InChI=1S/C15H28O3/c1-10(2)12-5-4-11(9-16)15(12)7-6-14(3,18)13(17)8-15/h10-13,16-18H,4-9H2,1-3H3/t11-,12+,13+,14-,15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of 11beta-HSD1 (unknown origin) using cortisol as substrate assessed as NADPH formation by fluorescent plate reader analysis				Eur J Med Chem 110: 126-32 (2016) BindingDB Entry DOI: 10.7270/Q28P62DG
					More data for this Ligand-Target Pair