BDBM50145474 CHEMBL3764618

SMILES: [H][C@@]12O[C@]1([H])[C@@](C)(O)CC[C@]21[C@@H](CO)CC[C@H]1C(C)C

InChI Key: InChIKey=HCQILPTZDJSPJO-ULXLPNHUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145474   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50145474 (CHEMBL3764618) Show SMILES [H][C@@]12O[C@]1([H])[C@@](C)(O)CC[C@]21[C@@H](CO)CC[C@H]1C(C)C |r| Show InChI InChI=1S/C15H26O3/c1-9(2)11-5-4-10(8-16)15(11)7-6-14(3,17)12-13(15)18-12/h9-13,16-17H,4-8H2,1-3H3/t10-,11+,12+,13-,14+,15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of 11beta-HSD1 (unknown origin) using cortisol as substrate assessed as NADPH formation by fluorescent plate reader analysis				Eur J Med Chem 110: 126-32 (2016) BindingDB Entry DOI: 10.7270/Q28P62DG
					More data for this Ligand-Target Pair