BDBM50145972 2-Amino-4-[4-(5,7-dimethyl-2-propyl-imidazo[4,5-b]pyridin-3-ylmethyl)-phenyl]-quinoline-3-carboxylic acid::2-amino-4-(4-((5,7-dimethyl-2-propyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl)phenyl)quinoline-3-carboxylic acid::CHEMBL87327

SMILES: CCCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)-c1c(C(O)=O)c(N)nc2ccccc12

InChI Key: InChIKey=NDCNSIFWUFOHQO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50145972   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II type 1a (AT-1a) receptor (RABBIT)	BDBM50145972 (2-Amino-4-[4-(5,7-dimethyl-2-propyl-imidazo[4,5-b]...) Show SMILES CCCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)-c1c(C(O)=O)c(N)nc2ccccc12 Show InChI InChI=1S/C28H27N5O2/c1-4-7-22-32-25-16(2)14-17(3)30-27(25)33(22)15-18-10-12-19(13-11-18)23-20-8-5-6-9-21(20)31-26(29)24(23)28(34)35/h5-6,8-14H,4,7,15H2,1-3H3,(H2,29,31)(H,34,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Università di Siena Curated by ChEMBL					Assay Description Antagonist activity against AT1 receptor assessed as inhibition of Ang2-induced rabit aortic strip contraction				J Med Chem 49: 6451-64 (2006) Article DOI: 10.1021/jm0603163 BindingDB Entry DOI: 10.7270/Q2WW7H9J
					More data for this Ligand-Target Pair
Angiotensin II AT1B (RAT)	BDBM50145972 (2-Amino-4-[4-(5,7-dimethyl-2-propyl-imidazo[4,5-b]...) Show SMILES CCCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)-c1c(C(O)=O)c(N)nc2ccccc12 Show InChI InChI=1S/C28H27N5O2/c1-4-7-22-32-25-16(2)14-17(3)30-27(25)33(22)15-18-10-12-19(13-11-18)23-20-8-5-6-9-21(20)31-26(29)24(23)28(34)35/h5-6,8-14H,4,7,15H2,1-3H3,(H2,29,31)(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Università di Siena Curated by ChEMBL					Assay Description Binding affinity for rat angiotensin II receptor, type 1				J Med Chem 47: 2574-86 (2004) Article DOI: 10.1021/jm031100t BindingDB Entry DOI: 10.7270/Q25X28DX
					More data for this Ligand-Target Pair