BDBM50146171 CHEMBL3763399

SMILES: O=C(Nc1ccc2CCc3ccccc3N(C(=O)Cn3cccc3)c2c1)OC1CCCC1

InChI Key: InChIKey=UWOMENNJYIETEH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50146171   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor subfamily 1 group I member 3 (Homo sapiens (Human))	BDBM50146171 (CHEMBL3763399) Show SMILES O=C(Nc1ccc2CCc3ccccc3N(C(=O)Cn3cccc3)c2c1)OC1CCCC1 Show InChI InChI=1S/C26H27N3O3/c30-25(18-28-15-5-6-16-28)29-23-10-4-1-7-19(23)11-12-20-13-14-21(17-24(20)29)27-26(31)32-22-8-2-3-9-22/h1,4-7,10,13-17,22H,2-3,8-9,11-12,18H2,(H,27,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inverse agonist activity at GST tagged-human CAR-LBD assessed as reduction in fluorescein-PGC1 alpha coactivator recruitment after 1 hr by TR-FRET as...				Eur J Med Chem 108: 505-28 (2016) BindingDB Entry DOI: 10.7270/Q2BG2QV6
					More data for this Ligand-Target Pair