BDBM50146173 CHEMBL3763725

SMILES: O=C(Nc1ccc2CCc3ccccc3N(C(=O)Cn3cccc3)c2c1)OC1CC1

InChI Key: InChIKey=NTCFZAQAAVLMJU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50146173   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor subfamily 1 group I member 3 (Homo sapiens (Human))	BDBM50146173 (CHEMBL3763725) Show SMILES O=C(Nc1ccc2CCc3ccccc3N(C(=O)Cn3cccc3)c2c1)OC1CC1 Show InChI InChI=1S/C24H23N3O3/c28-23(16-26-13-3-4-14-26)27-21-6-2-1-5-17(21)7-8-18-9-10-19(15-22(18)27)25-24(29)30-20-11-12-20/h1-6,9-10,13-15,20H,7-8,11-12,16H2,(H,25,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inverse agonist activity at GST tagged-human CAR-LBD assessed as reduction in fluorescein-PGC1 alpha coactivator recruitment after 1 hr by TR-FRET as...				Eur J Med Chem 108: 505-28 (2016) BindingDB Entry DOI: 10.7270/Q2BG2QV6
					More data for this Ligand-Target Pair