BDBM50146174 CHEMBL3764583

SMILES: CC(C)(C)OC(=O)Nc1ccc2CCc3ccccc3N(C(=O)Cn3cccc3)c2c1

InChI Key: InChIKey=DZQVIGJRZBSOGB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50146174   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor subfamily 1 group I member 3 (Homo sapiens (Human))	BDBM50146174 (CHEMBL3764583) Show SMILES CC(C)(C)OC(=O)Nc1ccc2CCc3ccccc3N(C(=O)Cn3cccc3)c2c1 Show InChI InChI=1S/C25H27N3O3/c1-25(2,3)31-24(30)26-20-13-12-19-11-10-18-8-4-5-9-21(18)28(22(19)16-20)23(29)17-27-14-6-7-15-27/h4-9,12-16H,10-11,17H2,1-3H3,(H,26,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inverse agonist activity at GST tagged-human CAR-LBD assessed as reduction in fluorescein-PGC1 alpha coactivator recruitment after 1 hr by TR-FRET as...				Eur J Med Chem 108: 505-28 (2016) BindingDB Entry DOI: 10.7270/Q2BG2QV6
					More data for this Ligand-Target Pair