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SMILES: OC(=O)CC(NC(=O)C1CN(C(=O)C1)c1cccc(NC(=O)NCc2ccccc2)c1)c1ccccc1

InChI Key: InChIKey=AZFPXTNXYJUHOT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50146491   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Integrin alpha-V/beta-3


(Homo sapiens (Human))		BDBM50146491
PNG
(3-({1-[3-(3-Benzyl-ureido)-phenyl]-5-oxo-pyrrolidi...)
Show SMILES OC(=O)CC(NC(=O)C1CN(C(=O)C1)c1cccc(NC(=O)NCc2ccccc2)c1)c1ccccc1
Show InChI InChI=1S/C28H28N4O5/c33-25-14-21(27(36)31-24(16-26(34)35)20-10-5-2-6-11-20)18-32(25)23-13-7-12-22(15-23)30-28(37)29-17-19-8-3-1-4-9-19/h1-13,15,21,24H,14,16-18H2,(H,31,36)(H,34,35)(H2,29,30,37)
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Similars
Article
PubMed
 71n/an/an/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards vitronectin receptor (AlphaV-beta3 integrin).

Bioorg Med Chem Lett 14: 2905-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.03.033
BindingDB Entry DOI: 10.7270/Q2416WJD
More data for this
Ligand-Target Pair