BDBM50146946 CHEMBL3763449
SMILES: Oc1ccc(NC(=O)c2cc3cc(Cl)cc(Br)c3oc2=O)cc1
InChI Key: InChIKey=SSDSUWDVAFGJRG-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Factor XIIa (Homo sapiens (Human)) | BDBM50146946 (CHEMBL3763449) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Namur Curated by ChEMBL | Assay Description Inhibition of human factor 12a using S-2302 as substrate assessed as para-nitroaniline release preincubated for 10 mins followed by substrate additio... | Eur J Med Chem 110: 181-94 (2016) BindingDB Entry DOI: 10.7270/Q29G5PNX | |||||||||||
More data for this Ligand-Target Pair |