BDBM50147859 7-(cyclohexylamino)-2-phenyl-1,8-naphthyridin-4-ol::7-Cyclohexylamino-2-phenyl-[1,8]naphthyridin-4-ol::CHEMBL418797

SMILES: Oc1cc(nc2nc(NC3CCCCC3)ccc12)-c1ccccc1

InChI Key: InChIKey=ZDODJZMITPPZHF-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50147859   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine A1 receptor (BOVINE)	BDBM50147859 (7-(cyclohexylamino)-2-phenyl-1,8-naphthyridin-4-ol...) Show SMILES Oc1cc(nc2nc(NC3CCCCC3)ccc12)-c1ccccc1 Show InChI InChI=1S/C20H21N3O/c24-18-13-17(14-7-3-1-4-8-14)22-20-16(18)11-12-19(23-20)21-15-9-5-2-6-10-15/h1,3-4,7-8,11-13,15H,2,5-6,9-10H2,(H2,21,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Binding affinity against adenosine A1 receptor in bovine cortical membranes using [3H]-CHA as radioligand				J Med Chem 47: 3019-31 (2004) Article DOI: 10.1021/jm030977p BindingDB Entry DOI: 10.7270/Q2BC3Z07
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50147859 (7-(cyclohexylamino)-2-phenyl-1,8-naphthyridin-4-ol...) Show SMILES Oc1cc(nc2nc(NC3CCCCC3)ccc12)-c1ccccc1 Show InChI InChI=1S/C20H21N3O/c24-18-13-17(14-7-3-1-4-8-14)22-20-16(18)11-12-19(23-20)21-15-9-5-2-6-10-15/h1,3-4,7-8,11-13,15H,2,5-6,9-10H2,(H2,21,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Binding affinity against adenosine A2 receptor in human striatal membranes using [3H]-CGS-21,680 as radioligand				J Med Chem 47: 3019-31 (2004) Article DOI: 10.1021/jm030977p BindingDB Entry DOI: 10.7270/Q2BC3Z07
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50147859 (7-(cyclohexylamino)-2-phenyl-1,8-naphthyridin-4-ol...) Show SMILES Oc1cc(nc2nc(NC3CCCCC3)ccc12)-c1ccccc1 Show InChI InChI=1S/C20H21N3O/c24-18-13-17(14-7-3-1-4-8-14)22-20-16(18)11-12-19(23-20)21-15-9-5-2-6-10-15/h1,3-4,7-8,11-13,15H,2,5-6,9-10H2,(H2,21,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Binding affinity against adenosine A1 receptor in human cortical membranes using [3H]-CHA as radioligand				J Med Chem 47: 3019-31 (2004) Article DOI: 10.1021/jm030977p BindingDB Entry DOI: 10.7270/Q2BC3Z07
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50147859 (7-(cyclohexylamino)-2-phenyl-1,8-naphthyridin-4-ol...) Show SMILES Oc1cc(nc2nc(NC3CCCCC3)ccc12)-c1ccccc1 Show InChI InChI=1S/C20H21N3O/c24-18-13-17(14-7-3-1-4-8-14)22-20-16(18)11-12-19(23-20)21-15-9-5-2-6-10-15/h1,3-4,7-8,11-13,15H,2,5-6,9-10H2,(H2,21,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Binding affinity against adenosine A2 receptor in bovine striatal membranes using [3H]-CGS-21,680 as radioligand				J Med Chem 47: 3019-31 (2004) Article DOI: 10.1021/jm030977p BindingDB Entry DOI: 10.7270/Q2BC3Z07
					More data for this Ligand-Target Pair