BDBM50147881 7-Morpholin-4-yl-2-phenyl-[1,8]naphthyridin-4-ol::CHEMBL102491

SMILES: Oc1cc(nc2nc(ccc12)N1CCOCC1)-c1ccccc1

InChI Key: InChIKey=IYMKLWDSUIVPMJ-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50147881   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine A1 receptor (BOVINE)	BDBM50147881 (7-Morpholin-4-yl-2-phenyl-[1,8]naphthyridin-4-ol |...) Show SMILES Oc1cc(nc2nc(ccc12)N1CCOCC1)-c1ccccc1 Show InChI InChI=1S/C18H17N3O2/c22-16-12-15(13-4-2-1-3-5-13)19-18-14(16)6-7-17(20-18)21-8-10-23-11-9-21/h1-7,12H,8-11H2,(H,19,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Binding affinity against adenosine A1 receptor in bovine cortical membranes using [3H]-CHA as radioligand				J Med Chem 47: 3019-31 (2004) Article DOI: 10.1021/jm030977p BindingDB Entry DOI: 10.7270/Q2BC3Z07
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50147881 (7-Morpholin-4-yl-2-phenyl-[1,8]naphthyridin-4-ol |...) Show SMILES Oc1cc(nc2nc(ccc12)N1CCOCC1)-c1ccccc1 Show InChI InChI=1S/C18H17N3O2/c22-16-12-15(13-4-2-1-3-5-13)19-18-14(16)6-7-17(20-18)21-8-10-23-11-9-21/h1-7,12H,8-11H2,(H,19,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Binding affinity against adenosine A1 receptor in human cortical membranes using [3H]-CHA as radioligand				J Med Chem 47: 3019-31 (2004) Article DOI: 10.1021/jm030977p BindingDB Entry DOI: 10.7270/Q2BC3Z07
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50147881 (7-Morpholin-4-yl-2-phenyl-[1,8]naphthyridin-4-ol |...) Show SMILES Oc1cc(nc2nc(ccc12)N1CCOCC1)-c1ccccc1 Show InChI InChI=1S/C18H17N3O2/c22-16-12-15(13-4-2-1-3-5-13)19-18-14(16)6-7-17(20-18)21-8-10-23-11-9-21/h1-7,12H,8-11H2,(H,19,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Binding affinity against adenosine A2 receptor in human striatal membranes using [3H]-CGS-21,680 as radioligand				J Med Chem 47: 3019-31 (2004) Article DOI: 10.1021/jm030977p BindingDB Entry DOI: 10.7270/Q2BC3Z07
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50147881 (7-Morpholin-4-yl-2-phenyl-[1,8]naphthyridin-4-ol |...) Show SMILES Oc1cc(nc2nc(ccc12)N1CCOCC1)-c1ccccc1 Show InChI InChI=1S/C18H17N3O2/c22-16-12-15(13-4-2-1-3-5-13)19-18-14(16)6-7-17(20-18)21-8-10-23-11-9-21/h1-7,12H,8-11H2,(H,19,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Binding affinity against adenosine A2 receptor in bovine striatal membranes using [3H]-CGS-21,680 as radioligand				J Med Chem 47: 3019-31 (2004) Article DOI: 10.1021/jm030977p BindingDB Entry DOI: 10.7270/Q2BC3Z07
					More data for this Ligand-Target Pair