BDBM50147997 2-Cyclohexyl-N-(2-{4-[5-(2,3-dichloro-phenyl)-1-methyl-1H-pyrazol-3-yl]-piperidin-1-yl}-2-oxo-ethyl)-2-guanidino-acetamide::CHEMBL449094
SMILES: [#6]-n1nc(cc1-c1cccc(Cl)c1Cl)-[#6]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](\[#7]=[#6](/[#7])-[#7])-[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1
InChI Key: InChIKey=LJMYIEPLFHMHEH-XMMPIXPASA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Interleukin-2 receptor alpha chain (Mus musculus) | BDBM50147997 (2-Cyclohexyl-N-(2-{4-[5-(2,3-dichloro-phenyl)-1-me...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunesis Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assay | J Med Chem 47: 3111-30 (2004) Article DOI: 10.1021/jm049967u BindingDB Entry DOI: 10.7270/Q2TQ6280 | |||||||||||
More data for this Ligand-Target Pair |