BDBM50148069 (Z)-5'-Methyl-1H,1'H-[2,3']biindolylidene-3,2'-dione::5'-Methyl-1H,1'H-[2,3']biindolylidene-3,2'-dione::CHEMBL111433

SMILES: Cc1ccc2[nH]c(O)c(C3=Nc4ccccc4C3=O)c2c1

InChI Key: InChIKey=AOHZJKSTSDMBIZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50148069   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-Dependent Kinase 5 (CDK5) (Homo sapiens (Human))	BDBM50148069 ((Z)-5'-Methyl-1H,1'H-[2,3']biindolylidene-3,2'-dio...) Show SMILES Cc1ccc2[nH]c(O)c(C3=Nc4ccccc4C3=O)c2c1 |t:9| Show InChI InChI=1S/C17H12N2O2/c1-9-6-7-13-11(8-9)14(17(21)19-13)15-16(20)10-4-2-3-5-12(10)18-15/h2-8,19,21H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Inhibition of Cyclin-dependent kinase 5-p35nck5a				J Med Chem 47: 3236-41 (2004) Article DOI: 10.1021/jm030561b BindingDB Entry DOI: 10.7270/Q21J9BHQ
					More data for this Ligand-Target Pair