BDBM50148089 2-Methyl-7-[3-(4-phenoxy-2-propyl-phenoxy)-propoxy]-chroman-2-carboxylic acid::CHEMBL324449

SMILES: CCCc1cc(Oc2ccccc2)ccc1OCCCOc1ccc2CCC(C)(Oc2c1)C(O)=O

InChI Key: InChIKey=REPLEBPTHZQCFG-UHFFFAOYSA-N

Data: 2 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50148089   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50148089 (2-Methyl-7-[3-(4-phenoxy-2-propyl-phenoxy)-propoxy...) Show SMILES CCCc1cc(Oc2ccccc2)ccc1OCCCOc1ccc2CCC(C)(Oc2c1)C(O)=O Show InChI InChI=1S/C29H32O6/c1-3-8-22-19-25(34-23-9-5-4-6-10-23)13-14-26(22)33-18-7-17-32-24-12-11-21-15-16-29(2,28(30)31)35-27(21)20-24/h4-6,9-14,19-20H,3,7-8,15-18H2,1-2H3,(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency of PPAR gene activation against human PPAR gamma receptor using chimeric Gal4-hPPAR transactivation assay (TA)				J Med Chem 47: 3255-63 (2004) Article DOI: 10.1021/jm030621d BindingDB Entry DOI: 10.7270/Q2JW8DB1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50148089 (2-Methyl-7-[3-(4-phenoxy-2-propyl-phenoxy)-propoxy...) Show SMILES CCCc1cc(Oc2ccccc2)ccc1OCCCOc1ccc2CCC(C)(Oc2c1)C(O)=O Show InChI InChI=1S/C29H32O6/c1-3-8-22-19-25(34-23-9-5-4-6-10-23)13-14-26(22)33-18-7-17-32-24-12-11-21-15-16-29(2,28(30)31)35-27(21)20-24/h4-6,9-14,19-20H,3,7-8,15-18H2,1-2H3,(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity for human peroxisome proliferator activated receptor gamma using scintillation proximity assay (SPA)				J Med Chem 47: 3255-63 (2004) Article DOI: 10.1021/jm030621d BindingDB Entry DOI: 10.7270/Q2JW8DB1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50148089 (2-Methyl-7-[3-(4-phenoxy-2-propyl-phenoxy)-propoxy...) Show SMILES CCCc1cc(Oc2ccccc2)ccc1OCCCOc1ccc2CCC(C)(Oc2c1)C(O)=O Show InChI InChI=1S/C29H32O6/c1-3-8-22-19-25(34-23-9-5-4-6-10-23)13-14-26(22)33-18-7-17-32-24-12-11-21-15-16-29(2,28(30)31)35-27(21)20-24/h4-6,9-14,19-20H,3,7-8,15-18H2,1-2H3,(H,30,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency of PPAR gene activation against human Peroxisome proliferator activated receptor alpha using chimeric Gal4-hPPAR transactivation ass...				J Med Chem 47: 3255-63 (2004) Article DOI: 10.1021/jm030621d BindingDB Entry DOI: 10.7270/Q2JW8DB1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50148089 (2-Methyl-7-[3-(4-phenoxy-2-propyl-phenoxy)-propoxy...) Show SMILES CCCc1cc(Oc2ccccc2)ccc1OCCCOc1ccc2CCC(C)(Oc2c1)C(O)=O Show InChI InChI=1S/C29H32O6/c1-3-8-22-19-25(34-23-9-5-4-6-10-23)13-14-26(22)33-18-7-17-32-24-12-11-21-15-16-29(2,28(30)31)35-27(21)20-24/h4-6,9-14,19-20H,3,7-8,15-18H2,1-2H3,(H,30,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity for human peroxisome proliferator activated receptor alpha using scintillation proximity assay (SPA)				J Med Chem 47: 3255-63 (2004) Article DOI: 10.1021/jm030621d BindingDB Entry DOI: 10.7270/Q2JW8DB1
					More data for this Ligand-Target Pair