BDBM50149105 2-Phenyl-5-propyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine::CHEMBL124137

SMILES: CCCc1nc2n[nH]cc2c2nc(nn12)-c1ccccc1

InChI Key: InChIKey=KOSSEJPYQJHMFH-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50149105   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50149105 (2-Phenyl-5-propyl-7H-pyrazolo[4,3-e][1,2,4]triazol...) Show SMILES CCCc1nc2n[nH]cc2c2nc(nn12)-c1ccccc1 Show InChI InChI=1S/C15H14N6/c1-2-6-12-17-14-11(9-16-19-14)15-18-13(20-21(12)15)10-7-4-3-5-8-10/h3-5,7-9H,2,6H2,1H3,(H,16,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>120	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Factory, Inc. Curated by ChEMBL					Assay Description Displacement of specific [3H]-CGS- 21680 binding at human adenosine A2A receptor expressed in HEK-293 cells				Bioorg Med Chem Lett 14: 3775-9 (2004) Article DOI: 10.1016/j.bmcl.2004.04.099 BindingDB Entry DOI: 10.7270/Q21R6PZM
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50149105 (2-Phenyl-5-propyl-7H-pyrazolo[4,3-e][1,2,4]triazol...) Show SMILES CCCc1nc2n[nH]cc2c2nc(nn12)-c1ccccc1 Show InChI InChI=1S/C15H14N6/c1-2-6-12-17-14-11(9-16-19-14)15-18-13(20-21(12)15)10-7-4-3-5-8-10/h3-5,7-9H,2,6H2,1H3,(H,16,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>38	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Factory, Inc. Curated by ChEMBL					Assay Description Displacement of specific [3H]-DPCPX binding at human adenosine A1 receptor expressed in CHO cells.				Bioorg Med Chem Lett 14: 3775-9 (2004) Article DOI: 10.1016/j.bmcl.2004.04.099 BindingDB Entry DOI: 10.7270/Q21R6PZM
					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM50149105 (2-Phenyl-5-propyl-7H-pyrazolo[4,3-e][1,2,4]triazol...) Show SMILES CCCc1nc2n[nH]cc2c2nc(nn12)-c1ccccc1 Show InChI InChI=1S/C15H14N6/c1-2-6-12-17-14-11(9-16-19-14)15-18-13(20-21(12)15)10-7-4-3-5-8-10/h3-5,7-9H,2,6H2,1H3,(H,16,19)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Factory, Inc. Curated by ChEMBL					Assay Description Displacement of specific [3H]-DPCPX binding at human adenosine A2B receptor expressed in HEK-293 cells.				Bioorg Med Chem Lett 14: 3775-9 (2004) Article DOI: 10.1016/j.bmcl.2004.04.099 BindingDB Entry DOI: 10.7270/Q21R6PZM
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50149105 (2-Phenyl-5-propyl-7H-pyrazolo[4,3-e][1,2,4]triazol...) Show SMILES CCCc1nc2n[nH]cc2c2nc(nn12)-c1ccccc1 Show InChI InChI=1S/C15H14N6/c1-2-6-12-17-14-11(9-16-19-14)15-18-13(20-21(12)15)10-7-4-3-5-8-10/h3-5,7-9H,2,6H2,1H3,(H,16,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Factory, Inc. Curated by ChEMBL					Assay Description Displacement of specific [125I]-AB-MECA binding at human adenosine A3 receptor expressed in HEK-293 cells				Bioorg Med Chem Lett 14: 3775-9 (2004) Article DOI: 10.1016/j.bmcl.2004.04.099 BindingDB Entry DOI: 10.7270/Q21R6PZM
					More data for this Ligand-Target Pair