BDBM50149195 1-Benzyl-2,3-dihydro-1H-indole-5-carboxylic acid [(S)-1-((S)-2-hydroxy-tetrahydro-furan-3-ylcarbamoyl)-3-methyl-butyl]-amide::CHEMBL333995
SMILES: CC(C)C[C@H](NC(=O)c1ccc2N(Cc3ccccc3)CCc2c1)C(=O)N[C@H]1CCOC1O
InChI Key: InChIKey=BLQKVVSYQJRJSW-PFXBLUCKSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Calpain1 (Homo sapiens (Human)) | BDBM50149195 (1-Benzyl-2,3-dihydro-1H-indole-5-carboxylic acid [...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Inhibitory activity against on human calpain 1 | Bioorg Med Chem Lett 14: 3825-8 (2004) Article DOI: 10.1016/j.bmcl.2004.04.105 BindingDB Entry DOI: 10.7270/Q2NK3DH6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain1 (Homo sapiens (Human)) | BDBM50149195 (1-Benzyl-2,3-dihydro-1H-indole-5-carboxylic acid [...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Inhibitory activity against on calpain in C6 glial cells | Bioorg Med Chem Lett 14: 3825-8 (2004) Article DOI: 10.1016/j.bmcl.2004.04.105 BindingDB Entry DOI: 10.7270/Q2NK3DH6 | |||||||||||
More data for this Ligand-Target Pair |