BDBM50149653 CHEMBL182595::[3-(5-Amino-3-methyl-pyridin-2-yl)-2,5-dimethyl-pyrazolo[1,5-a]pyrimidin-7-yl]-dipropyl-amine

SMILES: CCCN(CCC)c1cc(C)nc2c(c(C)nn12)-c1ncc(N)cc1C

InChI Key: InChIKey=MBANSLYUPGYBGU-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50149653   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50149653 (CHEMBL182595 | [3-(5-Amino-3-methyl-pyridin-2-yl)-...) Show SMILES CCCN(CCC)c1cc(C)nc2c(c(C)nn12)-c1ncc(N)cc1C |(6.99,-.28,;5.47,-.05,;4.89,1.35,;3.35,1.56,;2.76,2.98,;3.7,4.2,;3.11,5.64,;2.41,.33,;3,-1.08,;2.06,-2.31,;2.65,-3.74,;.55,-2.1,;-.04,-.68,;-1.49,-.17,;-1.45,1.37,;-2.65,2.3,;.03,1.8,;.9,.53,;-2.89,-.84,;-2.89,-2.39,;-4.22,-3.18,;-5.55,-2.39,;-6.88,-3.18,;-5.55,-.85,;-4.22,-.05,;-4.23,1.46,)| Show InChI InChI=1S/C20H28N6/c1-6-8-25(9-7-2)17-11-14(4)23-20-18(15(5)24-26(17)20)19-13(3)10-16(21)12-22-19/h10-12H,6-9,21H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptor				J Med Chem 47: 4787-98 (2004) Article DOI: 10.1021/jm040058e BindingDB Entry DOI: 10.7270/Q2N29WDR
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50149653 (CHEMBL182595 | [3-(5-Amino-3-methyl-pyridin-2-yl)-...) Show SMILES CCCN(CCC)c1cc(C)nc2c(c(C)nn12)-c1ncc(N)cc1C |(6.99,-.28,;5.47,-.05,;4.89,1.35,;3.35,1.56,;2.76,2.98,;3.7,4.2,;3.11,5.64,;2.41,.33,;3,-1.08,;2.06,-2.31,;2.65,-3.74,;.55,-2.1,;-.04,-.68,;-1.49,-.17,;-1.45,1.37,;-2.65,2.3,;.03,1.8,;.9,.53,;-2.89,-.84,;-2.89,-2.39,;-4.22,-3.18,;-5.55,-2.39,;-6.88,-3.18,;-5.55,-.85,;-4.22,-.05,;-4.23,1.46,)| Show InChI InChI=1S/C20H28N6/c1-6-8-25(9-7-2)17-11-14(4)23-20-18(15(5)24-26(17)20)19-13(3)10-16(21)12-22-19/h10-12H,6-9,21H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity for recombinant human CRF1 receptor				Bioorg Med Chem Lett 14: 3943-7 (2004) Article DOI: 10.1016/j.bmcl.2004.05.056 BindingDB Entry DOI: 10.7270/Q2KK9B7F
					More data for this Ligand-Target Pair