BDBM50149858 CHEMBL184996::{4-[2-(4-Methoxy-phenylsulfanyl)-phenyl]-piperazin-1-yl}-acetic acid

SMILES: COc1ccc(Sc2ccccc2N2CCN(CC(O)=O)CC2)cc1

InChI Key: InChIKey=WTOJCCONXJJYOX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50149858   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 1 (Homo sapiens (Human))	BDBM50149858 (CHEMBL184996 | {4-[2-(4-Methoxy-phenylsulfanyl)-ph...) Show SMILES COc1ccc(Sc2ccccc2N2CCN(CC(O)=O)CC2)cc1 Show InChI InChI=1S/C19H22N2O3S/c1-24-15-6-8-16(9-7-15)25-18-5-3-2-4-17(18)21-12-10-20(11-13-21)14-19(22)23/h2-9H,10-14H2,1H3,(H,22,23)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter				Bioorg Med Chem Lett 14: 4027-30 (2004) Checked by Author Article DOI: 10.1016/j.bmcl.2004.05.043 BindingDB Entry DOI: 10.7270/Q2DV1JBF
					More data for this Ligand-Target Pair