BDBM50150339 (S)-3-Hydroxy-4-{[4-((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-prop-1-ynyl-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)-phenyl]-methyl-amino}-butyric acid::CHEMBL361406
SMILES: CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(cc1)N(C)C[C@@H](O)CC(O)=O
InChI Key: InChIKey=GCPNKCRRGYTIOQ-AOJVJNHBSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50150339 ((S)-3-Hydroxy-4-{[4-((8S,11R,13S,14S,17S)-17-hydro...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of dexamethasone-induced glucocorticoid receptor mediated alkaline phosphatase activity | Bioorg Med Chem Lett 14: 4173-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.021 BindingDB Entry DOI: 10.7270/Q2FJ2HJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Progesterone receptor (Homo sapiens (Human)) | BDBM50150339 ((S)-3-Hydroxy-4-{[4-((8S,11R,13S,14S,17S)-17-hydro...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of human progesterone receptor | Bioorg Med Chem Lett 14: 4173-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.021 BindingDB Entry DOI: 10.7270/Q2FJ2HJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50150339 ((S)-3-Hydroxy-4-{[4-((8S,11R,13S,14S,17S)-17-hydro...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of [3H]dexamethasone binding to human glucocorticoid receptor | Bioorg Med Chem Lett 14: 4173-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.021 BindingDB Entry DOI: 10.7270/Q2FJ2HJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid (RAT) | BDBM50150339 ((S)-3-Hydroxy-4-{[4-((8S,11R,13S,14S,17S)-17-hydro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of dexamethasone-induced glucocorticoid receptor mediated tyrosine aminotransferase in rat hepatocytes | Bioorg Med Chem Lett 14: 4173-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.021 BindingDB Entry DOI: 10.7270/Q2FJ2HJ9 | |||||||||||
More data for this Ligand-Target Pair |