BDBM50150492 2-(5-Carbamimidoyl-2-{4-[1-(1-imino-ethyl)-piperidin-4-yloxy]-phenoxymethyl}-benzoimidazol-1-yl)-N-(1-phenyl-ethyl)-acetamide; dihydrochloride::CHEMBL536723

SMILES: CC(NC(=O)Cn1c(COc2ccc(OC3CCN(CC3)C(C)=N)cc2)nc2cc(ccc12)C(N)=N)c1ccccc1

InChI Key: InChIKey=BRSITPAOLUGYEZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50150492   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50150492 (2-(5-Carbamimidoyl-2-{4-[1-(1-imino-ethyl)-piperid...) Show SMILES CC(NC(=O)Cn1c(COc2ccc(OC3CCN(CC3)C(C)=N)cc2)nc2cc(ccc12)C(N)=N)c1ccccc1 Show InChI InChI=1S/C32H37N7O3/c1-21(23-6-4-3-5-7-23)36-31(40)19-39-29-13-8-24(32(34)35)18-28(29)37-30(39)20-41-25-9-11-26(12-10-25)42-27-14-16-38(17-15-27)22(2)33/h3-13,18,21,27,33H,14-17,19-20H2,1-2H3,(H3,34,35)(H,36,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory concentration against human Coagulation factor X				Bioorg Med Chem Lett 14: 4281-6 (2004) Article DOI: 10.1016/j.bmcl.2004.05.092 BindingDB Entry DOI: 10.7270/Q22808C7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50150492 (2-(5-Carbamimidoyl-2-{4-[1-(1-imino-ethyl)-piperid...) Show SMILES CC(NC(=O)Cn1c(COc2ccc(OC3CCN(CC3)C(C)=N)cc2)nc2cc(ccc12)C(N)=N)c1ccccc1 Show InChI InChI=1S/C32H37N7O3/c1-21(23-6-4-3-5-7-23)36-31(40)19-39-29-13-8-24(32(34)35)18-28(29)37-30(39)20-41-25-9-11-26(12-10-25)42-27-14-16-38(17-15-27)22(2)33/h3-13,18,21,27,33H,14-17,19-20H2,1-2H3,(H3,34,35)(H,36,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory concentration against Coagulation factor II				Bioorg Med Chem Lett 14: 4281-6 (2004) Article DOI: 10.1016/j.bmcl.2004.05.092 BindingDB Entry DOI: 10.7270/Q22808C7
					More data for this Ligand-Target Pair