BDBM50150789 2,6-dibromophenol::CHEMBL111507

SMILES: Oc1c(Br)cccc1Br

InChI Key: InChIKey=SSIZLKDLDKIHEV-UHFFFAOYSA-N

Data: 1 KI  2 IC50  2 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50150789   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA) (Sphingobium chlorophenolicum)	BDBM50150789 (2,6-dibromophenol | CHEMBL111507) Show SMILES Oc1c(Br)cccc1Br Show InChI InChI=1S/C6H4Br2O/c7-4-2-1-3-5(8)6(4)9/h1-3,9H	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Whitman College					Assay Description The rate of the enzymatic reaction was determined by measuring product formation by a spectrophotometric assay developed by Xun and co-worker with mo...				Biochemistry 50: 8899-913 (2011) Article DOI: 10.1021/bi200855m BindingDB Entry DOI: 10.7270/Q2W957SW
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-1/beta-2/gamma-2 (Homo sapiens (Human))	BDBM50150789 (2,6-dibromophenol | CHEMBL111507) Show SMILES Oc1c(Br)cccc1Br Show InChI InChI=1S/C6H4Br2O/c7-4-2-1-3-5(8)6(4)9/h1-3,9H	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	1.00E+8	n/a	n/a	n/a	n/a
University of Chicago Medical Center Curated by ChEMBL					Assay Description Potentiation of GABA responses at human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2				J Med Chem 45: 3210-21 (2002) BindingDB Entry DOI: 10.7270/Q2FN17DV
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-1/beta-2/gamma-2 (Homo sapiens (Human))	BDBM50150789 (2,6-dibromophenol | CHEMBL111507) Show SMILES Oc1c(Br)cccc1Br Show InChI InChI=1S/C6H4Br2O/c7-4-2-1-3-5(8)6(4)9/h1-3,9H	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	1.00E+8	n/a	n/a	n/a	n/a
University of Chicago Medical Center Curated by ChEMBL					Assay Description Direct activation of human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2				J Med Chem 45: 3210-21 (2002) BindingDB Entry DOI: 10.7270/Q2FN17DV
					More data for this Ligand-Target Pair
Arachidonate 15-lipoxygenase (Homo sapiens (Human))	BDBM50150789 (2,6-dibromophenol | CHEMBL111507) Show SMILES Oc1c(Br)cccc1Br Show InChI InChI=1S/C6H4Br2O/c7-4-2-1-3-5(8)6(4)9/h1-3,9H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibitory effect on human reticulocyte 15-lipoxygenase				J Med Chem 47: 4060-5 (2004) Article DOI: 10.1021/jm049872s BindingDB Entry DOI: 10.7270/Q2SX6CPV
					More data for this Ligand-Target Pair
12-Lipoxygenase (12-LOX) (Homo sapiens (Human))	BDBM50150789 (2,6-dibromophenol | CHEMBL111507) Show SMILES Oc1c(Br)cccc1Br Show InChI InChI=1S/C6H4Br2O/c7-4-2-1-3-5(8)6(4)9/h1-3,9H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibitory effect on human platelet 12-lipoxygenase				J Med Chem 47: 4060-5 (2004) Article DOI: 10.1021/jm049872s BindingDB Entry DOI: 10.7270/Q2SX6CPV
					More data for this Ligand-Target Pair