BDBM50151010 2-[3-(1,3,4,9-Tetrahydro-beta-carbolin-2-yl)-propyl]-3H-quinazolin-4-one::CHEMBL364763

SMILES: O=c1[nH]c(CCCN2CCc3c(C2)[nH]c2ccccc32)nc2ccccc12

InChI Key: InChIKey=KVSWJONATOQUSH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50151010   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50151010 (2-[3-(1,3,4,9-Tetrahydro-beta-carbolin-2-yl)-propy...) Show SMILES O=c1[nH]c(CCCN2CCc3c(C2)[nH]c2ccccc32)nc2ccccc12 Show InChI InChI=1S/C22H22N4O/c27-22-17-7-2-4-9-19(17)24-21(25-22)10-5-12-26-13-11-16-15-6-1-3-8-18(15)23-20(16)14-26/h1-4,6-9,23H,5,10-14H2,(H,24,25,27)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1				J Med Chem 47: 4151-4 (2004) Article DOI: 10.1021/jm0499256 BindingDB Entry DOI: 10.7270/Q21G0KQ6
					More data for this Ligand-Target Pair