BDBM50151023 2-[3-(4-Biphenyl-4-yl-3,6-dihydro-2H-pyridin-1-yl)-propyl]-3H-quinazolin-4-one::CHEMBL362762

SMILES: O=c1[nH]c(CCCN2CCC(=CC2)c2ccc(cc2)-c2ccccc2)nc2ccccc12

InChI Key: InChIKey=ZCFNRIXRIAHPJO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50151023   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50151023 (2-[3-(4-Biphenyl-4-yl-3,6-dihydro-2H-pyridin-1-yl)...) Show SMILES O=c1[nH]c(CCCN2CCC(=CC2)c2ccc(cc2)-c2ccccc2)nc2ccccc12 |c:10| Show InChI InChI=1S/C28H27N3O/c32-28-25-9-4-5-10-26(25)29-27(30-28)11-6-18-31-19-16-24(17-20-31)23-14-12-22(13-15-23)21-7-2-1-3-8-21/h1-5,7-10,12-16H,6,11,17-20H2,(H,29,30,32)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1				J Med Chem 47: 4151-4 (2004) Article DOI: 10.1021/jm0499256 BindingDB Entry DOI: 10.7270/Q21G0KQ6
					More data for this Ligand-Target Pair