BDBM50151184 5-[4-(3-Chloro-1-methyl-1H-pyrazol-4-ylmethyl)-piperazin-1-yl]-2-furan-2-yl-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-ylamine::CHEMBL189453

SMILES: Cn1cc(CN2CCN(CC2)c2nc(N)n3nc(nc3n2)-c2ccco2)c(Cl)n1

InChI Key: InChIKey=JDERYDAHOBOTQV-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50151184   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine Receptors A2a (A2a) (Rattus norvegicus (rat))	BDBM50151184 (5-[4-(3-Chloro-1-methyl-1H-pyrazol-4-ylmethyl)-pip...) Show SMILES Cn1cc(CN2CCN(CC2)c2nc(N)n3nc(nc3n2)-c2ccco2)c(Cl)n1 Show InChI InChI=1S/C17H19ClN10O/c1-25-9-11(13(18)23-25)10-26-4-6-27(7-5-26)16-21-15(19)28-17(22-16)20-14(24-28)12-3-2-8-29-12/h2-3,8-9H,4-7,10H2,1H3,(H2,19,20,21,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec, Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]-ZM-241,385 binidng to rat brain adenosine A2a receptor				J Med Chem 47: 4291-9 (2004) Article DOI: 10.1021/jm0498405 BindingDB Entry DOI: 10.7270/Q2805235
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50151184 (5-[4-(3-Chloro-1-methyl-1H-pyrazol-4-ylmethyl)-pip...) Show SMILES Cn1cc(CN2CCN(CC2)c2nc(N)n3nc(nc3n2)-c2ccco2)c(Cl)n1 Show InChI InChI=1S/C17H19ClN10O/c1-25-9-11(13(18)23-25)10-26-4-6-27(7-5-26)16-21-15(19)28-17(22-16)20-14(24-28)12-3-2-8-29-12/h2-3,8-9H,4-7,10H2,1H3,(H2,19,20,21,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec, Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]-DPCPX binding to rat cerebral cortex adenosine A1 receptor				J Med Chem 47: 4291-9 (2004) Article DOI: 10.1021/jm0498405 BindingDB Entry DOI: 10.7270/Q2805235
					More data for this Ligand-Target Pair