null
SMILES: Cc1[nH]c2cc(ccc2c1Oc1ccc(F)cc1)S(C)(=O)=O
InChI Key: InChIKey=VHSYYXRBWBHMNB-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin G/H synthase 1 (Homo sapiens (Human)) | BDBM50151760![]() (3-(4-Fluoro-phenoxy)-6-methanesulfonyl-2-methyl-1H...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Palo Alto Curated by ChEMBL | Assay Description Inhibitory concentration against human whole blood Prostaglandin G/H synthase 1 | Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50151760![]() (3-(4-Fluoro-phenoxy)-6-methanesulfonyl-2-methyl-1H...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Palo Alto Curated by ChEMBL | Assay Description In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity | Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50151760![]() (3-(4-Fluoro-phenoxy)-6-methanesulfonyl-2-methyl-1H...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Palo Alto Curated by ChEMBL | Assay Description Inhibitory concentration against human whole blood Prostaglandin G/H synthase 2 enzyme activity was determined | Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S | |||||||||||
More data for this Ligand-Target Pair |