BDBM50151955 4-{4-[4-(5-Methoxy-1H-indol-3-yl)-butyl]-piperazin-1-yl}-phenol::CHEMBL186173

SMILES: COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc(O)cc3)c2c1

InChI Key: InChIKey=QZPJXIWUORTZLP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50151955   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50151955 (4-{4-[4-(5-Methoxy-1H-indol-3-yl)-butyl]-piperazin...) Show SMILES COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc(O)cc3)c2c1 Show InChI InChI=1S/C23H29N3O2/c1-28-21-9-10-23-22(16-21)18(17-24-23)4-2-3-11-25-12-14-26(15-13-25)19-5-7-20(27)8-6-19/h5-10,16-17,24,27H,2-4,11-15H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cells				J Med Chem 47: 4677-83 (2004) Article DOI: 10.1021/jm040792y BindingDB Entry DOI: 10.7270/Q28S4PCR
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50151955 (4-{4-[4-(5-Methoxy-1H-indol-3-yl)-butyl]-piperazin...) Show SMILES COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc(O)cc3)c2c1 Show InChI InChI=1S/C23H29N3O2/c1-28-21-9-10-23-22(16-21)18(17-24-23)4-2-3-11-25-12-14-26(15-13-25)19-5-7-20(27)8-6-19/h5-10,16-17,24,27H,2-4,11-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone from dopamine D2 receptor of rat striatal membranes				J Med Chem 47: 4677-83 (2004) Article DOI: 10.1021/jm040792y BindingDB Entry DOI: 10.7270/Q28S4PCR
					More data for this Ligand-Target Pair