BDBM50151956 5-Methoxy-3-[4-(4-phenyl-piperazin-1-yl)-butyl]-1H-indole::CHEMBL186229

SMILES: COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccccc3)c2c1

InChI Key: InChIKey=BKPFUMLELZUBFG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50151956   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50151956 (5-Methoxy-3-[4-(4-phenyl-piperazin-1-yl)-butyl]-1H...) Show SMILES COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccccc3)c2c1 Show InChI InChI=1S/C23H29N3O/c1-27-21-10-11-23-22(17-21)19(18-24-23)7-5-6-12-25-13-15-26(16-14-25)20-8-3-2-4-9-20/h2-4,8-11,17-18,24H,5-7,12-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone from dopamine D2 receptor of rat striatal membranes				J Med Chem 47: 4677-83 (2004) Article DOI: 10.1021/jm040792y BindingDB Entry DOI: 10.7270/Q28S4PCR
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50151956 (5-Methoxy-3-[4-(4-phenyl-piperazin-1-yl)-butyl]-1H...) Show SMILES COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccccc3)c2c1 Show InChI InChI=1S/C23H29N3O/c1-27-21-10-11-23-22(17-21)19(18-24-23)7-5-6-12-25-13-15-26(16-14-25)20-8-3-2-4-9-20/h2-4,8-11,17-18,24H,5-7,12-16H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cells				J Med Chem 47: 4677-83 (2004) Article DOI: 10.1021/jm040792y BindingDB Entry DOI: 10.7270/Q28S4PCR
					More data for this Ligand-Target Pair