BDBM50151972 Acetic acid 4-{4-[4-(5-methoxy-1H-indol-3-yl)-butyl]-piperazin-1-yl}-phenyl ester::CHEMBL185899

SMILES: COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc(OC(C)=O)cc3)c2c1

InChI Key: InChIKey=FCBAMQJWCNMMEU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50151972   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50151972 (Acetic acid 4-{4-[4-(5-methoxy-1H-indol-3-yl)-buty...) Show SMILES COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc(OC(C)=O)cc3)c2c1 Show InChI InChI=1S/C25H31N3O3/c1-19(29)31-22-8-6-21(7-9-22)28-15-13-27(14-16-28)12-4-3-5-20-18-26-25-11-10-23(30-2)17-24(20)25/h6-11,17-18,26H,3-5,12-16H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cells				J Med Chem 47: 4677-83 (2004) Article DOI: 10.1021/jm040792y BindingDB Entry DOI: 10.7270/Q28S4PCR
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50151972 (Acetic acid 4-{4-[4-(5-methoxy-1H-indol-3-yl)-buty...) Show SMILES COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc(OC(C)=O)cc3)c2c1 Show InChI InChI=1S/C25H31N3O3/c1-19(29)31-22-8-6-21(7-9-22)28-15-13-27(14-16-28)12-4-3-5-20-18-26-25-11-10-23(30-2)17-24(20)25/h6-11,17-18,26H,3-5,12-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone from dopamine D2 receptor of rat striatal membranes				J Med Chem 47: 4677-83 (2004) Article DOI: 10.1021/jm040792y BindingDB Entry DOI: 10.7270/Q28S4PCR
					More data for this Ligand-Target Pair