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SMILES: CCCN(CCC)c1cc(C)nc2c(c(C)nn12)-c1ccc(C)nc1

InChI Key: InChIKey=CJUMKBYLDDALRW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50152168   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50152168
PNG
(CHEMBL362305 | [2,5-Dimethyl-3-(6-methyl-pyridin-3...)
Show SMILES CCCN(CCC)c1cc(C)nc2c(c(C)nn12)-c1ccc(C)nc1
Show InChI InChI=1S/C20H27N5/c1-6-10-24(11-7-2)18-12-15(4)22-20-19(16(5)23-25(18)20)17-9-8-14(3)21-13-17/h8-9,12-13H,6-7,10-11H2,1-5H3
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 21n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptor

J Med Chem 47: 4787-98 (2004)


Article DOI: 10.1021/jm040058e
BindingDB Entry DOI: 10.7270/Q2N29WDR
More data for this
Ligand-Target Pair