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SMILES: CCCN(CCC)c1cc(C)nc2c(c(C)nn12)-c1c(C)cc(nc1C)N(C)C

InChI Key: InChIKey=VSXXJLQNCKYOBZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152177   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50152177 (CHEMBL187039 | [3-(6-Dimethylamino-2,4-dimethyl-py...) Show SMILES CCCN(CCC)c1cc(C)nc2c(c(C)nn12)-c1c(C)cc(nc1C)N(C)C |(4,5.65,;4.49,4.17,;3.47,3.03,;3.96,1.57,;5.47,1.26,;6.5,2.4,;8,2.09,;2.92,.41,;3.41,-1.04,;2.39,-2.2,;2.87,-3.65,;.89,-1.87,;.41,-.41,;-1,.2,;-.86,1.75,;-2.01,2.76,;.66,2.06,;1.43,.72,;-2.33,-.58,;-3.68,.19,;-3.69,1.75,;-5.02,-.58,;-5.02,-2.13,;-3.68,-2.91,;-2.33,-2.13,;-1,-2.91,;-6.36,-2.91,;-7.68,-2.13,;-6.36,-4.45,)| Show InChI InChI=1S/C23H34N6/c1-9-11-28(12-10-2)20-14-16(4)24-23-22(18(6)26-29(20)23)21-15(3)13-19(27(7)8)25-17(21)5/h13-14H,9-12H2,1-8H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptor				J Med Chem 47: 4787-98 (2004) Article DOI: 10.1021/jm040058e BindingDB Entry DOI: 10.7270/Q2N29WDR
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50152177 (CHEMBL187039 | [3-(6-Dimethylamino-2,4-dimethyl-py...) Show SMILES CCCN(CCC)c1cc(C)nc2c(c(C)nn12)-c1c(C)cc(nc1C)N(C)C |(4,5.65,;4.49,4.17,;3.47,3.03,;3.96,1.57,;5.47,1.26,;6.5,2.4,;8,2.09,;2.92,.41,;3.41,-1.04,;2.39,-2.2,;2.87,-3.65,;.89,-1.87,;.41,-.41,;-1,.2,;-.86,1.75,;-2.01,2.76,;.66,2.06,;1.43,.72,;-2.33,-.58,;-3.68,.19,;-3.69,1.75,;-5.02,-.58,;-5.02,-2.13,;-3.68,-2.91,;-2.33,-2.13,;-1,-2.91,;-6.36,-2.91,;-7.68,-2.13,;-6.36,-4.45,)| Show InChI InChI=1S/C23H34N6/c1-9-11-28(12-10-2)20-14-16(4)24-23-22(18(6)26-29(20)23)21-15(3)13-19(27(7)8)25-17(21)5/h13-14H,9-12H2,1-8H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptor				J Med Chem 47: 4787-98 (2004) Article DOI: 10.1021/jm040058e BindingDB Entry DOI: 10.7270/Q2N29WDR
					More data for this Ligand-Target Pair