BDBM50153240 CHEMBL184418::N-(2-Diethylamino-ethyl)-2-methoxy-4-[3-(3-trifluoromethoxy-phenyl)-ureido]-benzamide
SMILES: CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2cccc(OC(F)(F)F)c2)cc1OC
InChI Key: InChIKey=VSRISVPSCMDVMK-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melanin-concentrating hormone receptor (Homo sapiens (Human)) | BDBM50153240 (CHEMBL184418 | N-(2-Diethylamino-ethyl)-2-methoxy-...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma A/S Curated by ChEMBL | Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using scintillation proximity ass... | Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT | |||||||||||
More data for this Ligand-Target Pair |