null

SMILES: Cn1cncc1C(OCc1cc(=O)c(cn1-c1cccc(Cl)c1)C#N)c1ccc(cc1)C#N

InChI Key: InChIKey=HTFGYEUMDFBWTG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153768   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50153768 (1-(3-Chloro-phenyl)-6-[(4-cyano-phenyl)-(3-methyl-...) Show SMILES Cn1cncc1C(OCc1cc(=O)c(cn1-c1cccc(Cl)c1)C#N)c1ccc(cc1)C#N Show InChI InChI=1S/C25H18ClN5O2/c1-30-16-29-13-23(30)25(18-7-5-17(11-27)6-8-18)33-15-22-10-24(32)19(12-28)14-31(22)21-4-2-3-20(26)9-21/h2-10,13-14,16,25H,15H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of Bovine geranylgeranyltransferase (GGT)				Bioorg Med Chem Lett 14: 5367-70 (2004) Article DOI: 10.1016/j.bmcl.2004.08.012 BindingDB Entry DOI: 10.7270/Q2NS0TC9
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50153768 (1-(3-Chloro-phenyl)-6-[(4-cyano-phenyl)-(3-methyl-...) Show SMILES Cn1cncc1C(OCc1cc(=O)c(cn1-c1cccc(Cl)c1)C#N)c1ccc(cc1)C#N Show InChI InChI=1S/C25H18ClN5O2/c1-30-16-29-13-23(30)25(18-7-5-17(11-27)6-8-18)33-15-22-10-24(32)19(12-28)14-31(22)21-4-2-3-20(26)9-21/h2-10,13-14,16,25H,15H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of Bovine farnesyltransferase (FTase)				Bioorg Med Chem Lett 14: 5367-70 (2004) Article DOI: 10.1016/j.bmcl.2004.08.012 BindingDB Entry DOI: 10.7270/Q2NS0TC9
					More data for this Ligand-Target Pair