Found 3 hits for monomerid = 50153769 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Bos taurus (bovine)) | BDBM50153769
![PNG](/data/jpeg/tenK5015/BindingDB_50153769.png) (5-(3-Chloro-phenyl)-6-({[3-(4-cyano-benzyl)-3H-imi...)Show SMILES Cn1c(CNCc2cncn2Cc2ccc(cc2)C#N)c(cc(C#N)c1=O)-c1cccc(Cl)c1 Show InChI InChI=1S/C26H21ClN6O/c1-32-25(24(10-21(12-29)26(32)34)20-3-2-4-22(27)9-20)15-30-13-23-14-31-17-33(23)16-19-7-5-18(11-28)6-8-19/h2-10,14,17,30H,13,15-16H2,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of Bovine farnesyltransferase (FTase) |
Bioorg Med Chem Lett 14: 5367-70 (2004)
Article DOI: 10.1016/j.bmcl.2004.08.012 BindingDB Entry DOI: 10.7270/Q2NS0TC9 |
More data for this Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Mus musculus) | BDBM50153769
![PNG](/data/jpeg/tenK5015/BindingDB_50153769.png) (5-(3-Chloro-phenyl)-6-({[3-(4-cyano-benzyl)-3H-imi...)Show SMILES Cn1c(CNCc2cncn2Cc2ccc(cc2)C#N)c(cc(C#N)c1=O)-c1cccc(Cl)c1 Show InChI InChI=1S/C26H21ClN6O/c1-32-25(24(10-21(12-29)26(32)34)20-3-2-4-22(27)9-20)15-30-13-23-14-31-17-33(23)16-19-7-5-18(11-28)6-8-19/h2-10,14,17,30H,13,15-16H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 21 | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of Ras farnesylation in H-Ras transformed NIH3T3 cells at 100 nM |
Bioorg Med Chem Lett 14: 5367-70 (2004)
Article DOI: 10.1016/j.bmcl.2004.08.012 BindingDB Entry DOI: 10.7270/Q2NS0TC9 |
More data for this Ligand-Target Pair | |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Bos taurus (bovine)) | BDBM50153769
![PNG](/data/jpeg/tenK5015/BindingDB_50153769.png) (5-(3-Chloro-phenyl)-6-({[3-(4-cyano-benzyl)-3H-imi...)Show SMILES Cn1c(CNCc2cncn2Cc2ccc(cc2)C#N)c(cc(C#N)c1=O)-c1cccc(Cl)c1 Show InChI InChI=1S/C26H21ClN6O/c1-32-25(24(10-21(12-29)26(32)34)20-3-2-4-22(27)9-20)15-30-13-23-14-31-17-33(23)16-19-7-5-18(11-28)6-8-19/h2-10,14,17,30H,13,15-16H2,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of Bovine geranylgeranyltransferase (GGT) |
Bioorg Med Chem Lett 14: 5367-70 (2004)
Article DOI: 10.1016/j.bmcl.2004.08.012 BindingDB Entry DOI: 10.7270/Q2NS0TC9 |
More data for this Ligand-Target Pair | |