BDBM50154231 8-Benzhydryl-4-(4-methoxy-phenyl)-1,4-diaza-bicyclo[3.3.1]nonane::CHEMBL280518

SMILES: COc1ccc(cc1)N1CCN2CC1CCC2C(c1ccccc1)c1ccccc1

InChI Key: InChIKey=RMIUMOINQIRNDK-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50154231   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50154231 (8-Benzhydryl-4-(4-methoxy-phenyl)-1,4-diaza-bicycl...) Show SMILES COc1ccc(cc1)N1CCN2CC1CCC2C(c1ccccc1)c1ccccc1 |TLB:5:8:12:16.15.14,THB:17:16:12:8.9.10| Show InChI InChI=1S/C27H30N2O/c1-30-25-15-12-23(13-16-25)29-19-18-28-20-24(29)14-17-26(28)27(21-8-4-2-5-9-21)22-10-6-3-7-11-22/h2-13,15-16,24,26-27H,14,17-20H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68.9	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to dopamine transporter of rat striatum				J Med Chem 47: 5101-13 (2004) Article DOI: 10.1021/jm049796t BindingDB Entry DOI: 10.7270/Q2HQ40P0
					More data for this Ligand-Target Pair
Norepinephrine Monoamine transporters (Rattus norvegicus)	BDBM50154231 (8-Benzhydryl-4-(4-methoxy-phenyl)-1,4-diaza-bicycl...) Show SMILES COc1ccc(cc1)N1CCN2CC1CCC2C(c1ccccc1)c1ccccc1 |TLB:5:8:12:16.15.14,THB:17:16:12:8.9.10| Show InChI InChI=1S/C27H30N2O/c1-30-25-15-12-23(13-16-25)29-19-18-28-20-24(29)14-17-26(28)27(21-8-4-2-5-9-21)22-10-6-3-7-11-22/h2-13,15-16,24,26-27H,14,17-20H2,1H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine binding to norepinephrine transporter of rat cerebral cortex				J Med Chem 47: 5101-13 (2004) Article DOI: 10.1021/jm049796t BindingDB Entry DOI: 10.7270/Q2HQ40P0
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50154231 (8-Benzhydryl-4-(4-methoxy-phenyl)-1,4-diaza-bicycl...) Show SMILES COc1ccc(cc1)N1CCN2CC1CCC2C(c1ccccc1)c1ccccc1 |TLB:5:8:12:16.15.14,THB:17:16:12:8.9.10| Show InChI InChI=1S/C27H30N2O/c1-30-25-15-12-23(13-16-25)29-19-18-28-20-24(29)14-17-26(28)27(21-8-4-2-5-9-21)22-10-6-3-7-11-22/h2-13,15-16,24,26-27H,14,17-20H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of [3H]citalopram binding to serotonin transporter of rat cerebral cortex				J Med Chem 47: 5101-13 (2004) Article DOI: 10.1021/jm049796t BindingDB Entry DOI: 10.7270/Q2HQ40P0
					More data for this Ligand-Target Pair