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SMILES: O=C1OCC\C1=C/c1ccc2OCCCc2c1

InChI Key: InChIKey=JZCVQLIASALOPP-FMIVXFBMSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50154354   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity tyrosine-phosphorylation-regulated kinase 2 (Homo sapiens (Human))	BDBM50154354 (CHEMBL3775193) Show SMILES O=C1OCC\C1=C/c1ccc2OCCCc2c1 Show InChI InChI=1S/C14H14O3/c15-14-12(5-7-17-14)9-10-3-4-13-11(8-10)2-1-6-16-13/h3-4,8-9H,1-2,5-7H2/b12-9+	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged DYRK2 expressed in Escherichia coli BL21(DE3) cells using KKISGRLSPIMTEQ-NH2 as substrate incub...				Eur J Med Chem 112: 209-16 (2016) BindingDB Entry DOI: 10.7270/Q2GF0WC4
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM50154354 (CHEMBL3775193) Show SMILES O=C1OCC\C1=C/c1ccc2OCCCc2c1 Show InChI InChI=1S/C14H14O3/c15-14-12(5-7-17-14)9-10-3-4-13-11(8-10)2-1-6-16-13/h3-4,8-9H,1-2,5-7H2/b12-9+	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of full length recombinant human GST-tagged DYRK1B expressed in insect cells using KKISGRLSPIMTEQ-NH2 as substrate incubated for 15 mins i...				Eur J Med Chem 112: 209-16 (2016) BindingDB Entry DOI: 10.7270/Q2GF0WC4
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50154354 (CHEMBL3775193) Show SMILES O=C1OCC\C1=C/c1ccc2OCCCc2c1 Show InChI InChI=1S/C14H14O3/c15-14-12(5-7-17-14)9-10-3-4-13-11(8-10)2-1-6-16-13/h3-4,8-9H,1-2,5-7H2/b12-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged CLK1 catalytic domain (129 to 484 residues) expressed in Escherichia coli using GRSRSRSRSRSRSRSR as substr...				Eur J Med Chem 112: 209-16 (2016) BindingDB Entry DOI: 10.7270/Q2GF0WC4
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50154354 (CHEMBL3775193) Show SMILES O=C1OCC\C1=C/c1ccc2OCCCc2c1 Show InChI InChI=1S/C14H14O3/c15-14-12(5-7-17-14)9-10-3-4-13-11(8-10)2-1-6-16-13/h3-4,8-9H,1-2,5-7H2/b12-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of EGFR (unknown origin) incubated for 15 mins in presence of [gamma-32P]ATP				Eur J Med Chem 112: 209-16 (2016) BindingDB Entry DOI: 10.7270/Q2GF0WC4
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50154354 (CHEMBL3775193) Show SMILES O=C1OCC\C1=C/c1ccc2OCCCc2c1 Show InChI InChI=1S/C14H14O3/c15-14-12(5-7-17-14)9-10-3-4-13-11(8-10)2-1-6-16-13/h3-4,8-9H,1-2,5-7H2/b12-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged DYRK1A catalytic domain expressed in Escherichia coli BL21(DE3) cells using KKISGRLSPIMTEQ-NH2...				Eur J Med Chem 112: 209-16 (2016) BindingDB Entry DOI: 10.7270/Q2GF0WC4
					More data for this Ligand-Target Pair