BDBM50154582 6-[1,3]Dioxan-2-yl-quinolin-2-ylamine::CHEMBL426622

SMILES: Nc1ccc2cc(ccc2n1)C1OCCCO1

InChI Key: InChIKey=QTYSUHTYOLPZNR-UHFFFAOYSA-N

Data: 1 Kd  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50154582   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase TEC (Mus musculus)	BDBM50154582 (6-[1,3]Dioxan-2-yl-quinolin-2-ylamine | CHEMBL4266...) Show SMILES Nc1ccc2cc(ccc2n1)C1OCCCO1 Show InChI InChI=1S/C13H14N2O2/c14-12-5-3-9-8-10(2-4-11(9)15-12)13-16-6-1-7-17-13/h2-5,8,13H,1,6-7H2,(H2,14,15)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a
The University of Adelaide Curated by ChEMBL					Assay Description Displacement of PRP-1 peptide from mouse Tec kinase SH3 domain by fluorescence polarization				J Med Chem 47: 5405-17 (2004) Article DOI: 10.1021/jm049533z BindingDB Entry DOI: 10.7270/Q26M369B
					More data for this Ligand-Target Pair
Tyrosine-protein kinase TEC (Mus musculus)	BDBM50154582 (6-[1,3]Dioxan-2-yl-quinolin-2-ylamine | CHEMBL4266...) Show SMILES Nc1ccc2cc(ccc2n1)C1OCCCO1 Show InChI InChI=1S/C13H14N2O2/c14-12-5-3-9-8-10(2-4-11(9)15-12)13-16-6-1-7-17-13/h2-5,8,13H,1,6-7H2,(H2,14,15)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	5.20E+4	n/a	n/a	n/a	n/a	n/a
The University of Adelaide Curated by ChEMBL					Assay Description Displacement of PRP-1 peptide from mouse Tec kinase SH3 domain by fluorescence polarization				J Med Chem 47: 5405-17 (2004) Article DOI: 10.1021/jm049533z BindingDB Entry DOI: 10.7270/Q26M369B
					More data for this Ligand-Target Pair
Nck adaptor protein 1 (Homo sapiens (Human))	BDBM50154582 (6-[1,3]Dioxan-2-yl-quinolin-2-ylamine | CHEMBL4266...) Show SMILES Nc1ccc2cc(ccc2n1)C1OCCCO1 Show InChI InChI=1S/C13H14N2O2/c14-12-5-3-9-8-10(2-4-11(9)15-12)13-16-6-1-7-17-13/h2-5,8,13H,1,6-7H2,(H2,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a
The University of Adelaide Curated by ChEMBL					Assay Description Displacement of PRP-1 peptide from human Nck kinase SH3 domain by fluorescence polarization				J Med Chem 47: 5405-17 (2004) Article DOI: 10.1021/jm049533z BindingDB Entry DOI: 10.7270/Q26M369B
					More data for this Ligand-Target Pair